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ZFM
(redirected from zinc finger motif)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.01 sec.
AcronymDefinition
ZFMZona Franca de Manaus
ZFMZentrum fuer Mikrotechnologien (German: Center for Microtechnologies)
ZFMZona Franca de Montevideo (Spanish: Montevideo Frank Zone; Uruguay)
ZFMZimbabwe Freedom Movement
ZFMZentralamt Fuer Mobilfunk (German: National Board for Mobile Communications)
ZFMZinc Finger Motif (immunology)
ZFMZone de Forte Mixité (French: Strong Mixed Zone; Belgium)


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Kupe virus L segment ORF also contains several protein motifs previously identified in DUGV and CCHFV, including an ovarian tumor-like cysteine protease domain, a DNA topoisomerase-like domain (aa 76--94), and a C2H2-type zinc finger motif (aa 608-631) (17,18).
A finger-like structure, known as a zinc finger motif, stabilizes the structure of a number of proteins.
Some of the targets that might be important include structural elements (such as the highly conserved zinc finger motif of the HIV nucleocapsid or the viral enzymes integrase and RNase H), regulatory and accessory proteins, processes (such as transcription, nuclear import and export of viral nucleic acid, and macromolecular interactions), and host targets (adhesion molecules, transcription factors, apoptosis, and signaling pathways).
 
 
 
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