1CTPCarboxy-Terminal Telopeptide of Type 1 Collagen
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One possible explanation for the absence of significant changes in blood osteocalcin, Alk-Ph and 1CTP concentrations after exercise in young rats in our study and in other exercise studies in young mice [29-32] might be due to the age of the rats or the localised effect of jumping exercise, which is limited to the hind limbs only, although the latter reason is somewhat contradicted by the finding of lower serum 1CTP concentrations following further continuous exercise (Table 2 and Fig.
Secondly, a negative relationship was observed in serum 1CTP, which reflects decreased bone resorption with increasing workload.
It also appears that significant increases in bone mass in young rats following 8STP might not always be reflected by changes in serum levels of osteocalcin, Alk-Ph and 1CTP. However, measurement of these parameters, particularly 1CTP, might be more useful when evaluating the maintenance of bone gains after bone loading.