HMGR

(redirected from 3-Hydroxy-3-Methylglutaryl-CoA Reductase)
AcronymDefinition
HMGR3-Hydroxy-3-Methylglutaryl-CoA Reductase (enzyme)
HMGRHealthy Marriages Grand Rapids (Grand Rapids, MI)
References in periodicals archive ?
Previous studies have shown that LDL-C--lowering alleles in 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), [4] the gene encoding the target of statins, are associated with lower risk of coronary heart disease (CHD), but also an increased risk of T2D.
Leveraging Human Genetics to Understand the Relation of LDL Cholesterol with Type 2 Diabetes
copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities," European Journal of Biochemistry/FEBS, vol.
Cholesterol Synthesis Increased in the MMI-Induced Subclinical Hypothyroidism Mice Model
Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids.
The effect of bergamot on dyslipidemia
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.
Short-term Rosuvastatin Treatment for the Prevention of Contrast-induced Acute Kidney Injury in Patients Receiving Moderate or High Volumes of Contrast Media: A Sub-analysis of the TRACK-D Study
The lobster mandibular organ produces soluble and membrane-bound forms of 3-hydroxy-3-methylglutaryl-CoA reductase. Biochem.
Hemolymph levels of methyl farnesoate during ovarian development of the swimming crab portunus trituberculatus, and its relation to transcript levels of HMG-CoA reductase and farnesoic acid O-Methyltransferase
Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts.
EFFECTS OF MATERNAL FOLIC ACID SUPPLEMENTATION AND INTRAUTERINE GROWTH RETARDATION ON EPIGENETIC MODIFICATION OF HEPATIC GENE EXPRESSION AND LIPID METABOLISM IN PIGLETS
The primary goal was to inhibit the enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) responsible for cholesterol biosynthesis in the body.
Statins in periodontal regeneration --the current scenario
This question is particularly relevant as the expression of the low-density lipoprotein receptor that is responsible for the intracellular uptake of cholesterol is regulated by mTOR,[sup.56] an active signaling pathway in RCC.[sup.57] Statins are synthetic agents that inhibit the rate-limiting enzyme of the mevalonate pathway, 3-hydroxy-3-methylglutaryl-CoA reductase, thereby inhibiting cholesterol biosynthesis.[sup.58] Recently, it has been suggested that statins may have activity against RCC.
Metabolic features of clear-cell renal cell carcinoma: mechanisms and clinical implications
HMG-CoA reductase (or 3-hydroxy-3-methylglutaryl-CoA reductase or HMGR) is the rate controlling enzyme (EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids.
HMG CoA reductase and hepatocytic hyperlipidemia in various oil fed rats
Genes spotted multiple times on different parts of the array include 3-hydroxy-3-methylglutaryl-CoA reductase, glycosylate reductase, choriogenin 2, a clone that shares homology to Unknown protein (GenBank accession no.
Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray. (Article)
Several loci have been associated with LDL-c lowering: apolipoprotein E (APOE), [4] a solute carrier organic anion transporter family member 1B1 (SLC01B1), lipoprotein(a) (LPA), and sortilin 1 (S0RT1); other genes with inconsistent associations with LDL-c response include ATP binding cassette subfamily B member 1 (ABCB1), ATP binding cassette subfamily G member 2 (ABCG2), and 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), though these will not be covered here.
Use of Pharmacogenetic Information in the Treatment of Cardiovascular Disease
Partial cloning, tissue distribution and effects of epigallocatechin gallate on hepatic 3-hydroxy-3-methylglutaryl-CoA reductase mRNA transcripts in goldfish ( Carassius auratus ).
Long Non-coding RNAs Expression Profile in HepG2 Cells Reveals the Potential Role of Long Non-coding RNAs in the Cholesterol Metabolism
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