HAD

(redirected from 3-Hydroxyacyl-CoA Dehydrogenase)
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AcronymDefinition
HADHIV (Human Immunodeficiency Virus) Associated Dementia
HADHospitalisation à Domicile (French: Home Hospitalization)
HADHome Affairs Department (Hong Kong)
HADHole Accumulation Diode (Sony)
HADHole Accumulated Diode (Sony)
HADHuman Adenovirus (pathogen)
HADHumanitarian Aid & Development (various locations)
HADHearing Aid Dispenser
HADHole Accumulation Diode
HAD3-Hydroxyacyl-CoA Dehydrogenase (deficiency)
HADHarrow Association of Disabled (UK)
HADHealth Assessment Document
HADHemadsorption (laboratory virus testing)
HADHebrew Association of the Deaf (Philadelphia, PA)
HADHuman Adjuvant Disease
HADAtlantic Haddock
HADHospital Anxiety Depression
HADHomeland Air Defense
HADHardware Data Acquisition
HADHubble Data Archive
HADHeadbangers Against Disco
HADHalmstad, Sweden - Halmstad (Airport Code)
HADHeinemann Australian Dictionary
HADHigh Availability Device
HADHeat Activated Device
HADHigh Aluminum Defect
HADHarness Assembly Drawing (electrical wire assembly drawing for manufacturing of cable harness assemblies)
HADHeat Acquisition Devices
HADHorizontal Acoustic Depiction
HADHeated Air Ducting
References in periodicals archive ?
Palladino et al., "Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase," The Journal of Biological Chemistry, vol.
Leucine-sensitive hyperinsulinaemic hypoglycaemia in patients with loss of function mutations in 3-Hydroxyacyl-CoA Dehydrogenase. Orphanet J Rare Dis 2012;7:25.
"In 2008 my son, Christopher, was picked up by newborn screening with a rare inherited disorder called LCHAD (long-chain "3-hydroxyacyl-CoA dehydrogenase deficiency) where his body cannot breakdown long-chain fatty acids.
Dietary Management of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD).
The enzymes for the b-oxidation oflong- to mediumchain fatty acids (C-18 to C-12) are located close to the inner mitochondrial membrane, they are: very-longchain acyl-CoA dehydrogenase, long-chain enoyl-CoA hydratase, long-chain L 3-hydroxyacyl-CoA dehydrogenase and long-chain 3-ketoacyl-CoA thiolase.
Peroxisomal bifunctional protein from rat liver is a trifunctional enzyme possessing 2-Enoyl-CoA hydratase, 3-Hydroxyacyl-CoA dehydrogenase, and [[DELTA].sup.3],[[DELTA].sup.2]-Enoyl-CoA isomerase activities.
Likewise, enzyme activities of 3-hydroxyacyl-CoA dehydrogenase and carnityl palmitoyl-CoA transferase are good indicators of lipid metabolism.
Mutations in 6 genes have been associated with HI (Table 1): the sulfonylurea receptor 1 (SUR-1; encoded by ABCC8) [2] (6); potassium inward rectifying channel (Kir6.2; encoded by KCNJ11) (7); glucokinase (GK; encoded by GCK) (8); glutamate dehydrogenase (GDH; encoded by GLUD-1) (9); short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD; encoded by HADH) (10); and ectopic expression on [beta]-cell plasma membrane of SLC16A1 [encodes monocarboxylate transporter 1 (MCT1)] (11).
The disease has been associated with a deficiency of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD).
In our previous research using comparative proteomic techniques, we observed that the expression of acetyl-Coenzyme A acetyltransferase 2 and 3-hydroxyacyl-CoA dehydrogenase type-2, those enzymes involved in fatty acid degradation, were decreased in the liver tissues of ketotic cows, which suggested that the ability to utilize fatty acids to produce C[O.sub.2], [H.sub.2]O and ATP was decreased (Xu and Wang, 2008).
(35.) PRZYREMBEL, H; JAKOBS, C; IJLST, L; DE KLERK, J.B.C.; WANDERS, R.J.A; Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.
The 3 enzymes involved are long-chain enoyl-CoA hydratase (LCEH), long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD), and long-chain 3-ketoacyl-CoA thiolase (LCTH).