3D-CRT3D Conformal Radiation Therapy
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In this study, we aim to compare target tissue and critical organ doses in 3D-CRT and IMRT plans in RT patients with early-stage left-sided breast cancer, which is receiving radiotherapy on the left chest wall.
3D-CRT manages to overcome the disadvantages induced by large T-shaped field of postoperative prophylactic radiotherapy, such as high tumor residual rate because of unsatisfactory dose distribution.
Hypofractionated radiotherapy provides a better quality of life, because it is a short duration treatment and shows comparable skin toxicities with that of Conventional Radiotherapy, more so if advanced treatment techniques like FIF 3D-CRT and IMRT are used.
The first phase of the 3D-CRT technique consisted of two no-coplanar tangential beams at 304[degrees] and 129[degrees] gantry angles, with collimator angle at 10[degrees] and 350[degrees], respectively.
Treatments consisted of standard three-dimensional conformal RT (3D-CRT) for the prostate in 74 patients, whole-pelvis RT (WP-RT) followed by 3D conformal prostate boost in seven, and salvage/adjuvant 3D-CRT for the postsurgical site after radical prostatectomy in 23 patients.
For each parotid, [D.sub.min], [D.sub.max] and [D.sub.mean] were evaluated comparatively between IMRT, VMAT and 3D-CRT techniques.
Five different dose plans (3D-CRT, IMRT, [SIB-IMRT.sub.2.3], [SIB-IMRT.sub.2.5], and [SIB-IMRT.sub.2.7]) were generated for each patient.
Data on 120 patients randomized to date were presented, of whom 58 had received conventional 3D-CRT, and 62 who had undergone IG-IMRT and received 50 Gy of radiation given in 24 fractions over 5 weeks.
Of the remaining 16, 9 had 3D-CRT (66 cGy, 33 fractions), 5 had intensity-modulated radiation therapy (IMRT) (66 cGy, 33 fractions and 46 cGy, 23 fractions), 1 had 3D-CRT at 79cGy, 42 fractions and 1 patient had 3D-CRT at 50 cGy, 25 fractions.
RayStation 4.0 also contains numerous improvements and additions throughout the system such as several added features in 3D-CRT planning including support for static arcs.
We compared the outcomes of patients treated using 3D-CRT and IMRT and the effect of cranial nerve involvement.