By defining and agreeing upon a clear set of metrics for measuring digital ad engagement that are comparable to other media and can measure uniquely interactive constructs of digital brand ads, we have reached a significant milestone in the 3MS
Cognitive function was measured using the 3MS
at baseline and at 3, 5, and 8 years, and cytokines IL-6, CRP, and TNF-[alpha] were used as serum markers of inflammation.
A score of less than 80 on the 3MS
is indicative of cognitive impairment; 39.
6 years (range 65-104 years) The 3MS
scores for these subjects ranged from 0 to 100 (mean 55.
was developed from Folstein's Mini-Mental State examination, a screening test for dementia with demonstrated reliability and validity.
The researchers identified four food groups that were independently associated with better 3MS
scores: dairy, vegetables, whole grains, and nuts and beans.
A psychometrician, blind to the specific 3MS
score administered neuropsychological tests to all subjects who scored 50 or more on the 3MS
During serial testing over the course of 4 years of prospective follow-up, however, those with metabolic syndrome experienced a significantly greater rate of decline in 3MS
scores than those free of the syndrome.
After closer examination of the data, the participants with metabolic syndrome who were in the high-inflammation sub-group averaged a roughly 1 point/year faster decline in 3MS
scores, compared with those without metabolic syndrome or those with metabolic syndrome but with a low level of systemic inflammation, Dr.
After the data were examined more closely, participants with metabolic syndrome who were in the high-inflammation subgroup averaged a roughly 1-point per year faster decline in 3MS
scores, compared with those without metabolic syndrome or those with metabolic syndrome but with a low level of systemic inflammation.
And the Trail Making Test Part B, a commonly used measure of executive function, turns out to have more predictive value than the 3MS
, said Dr.
Another 5% showed impaired global cognition based upon a 3MS
score below 23, but not impaired executive function.