5-FU

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Acronym	Definition
5-FU	5-Fluorouracil (drug used against pancreatic cancer)

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Hamsters were randomly assigned into six groups (n=6/ group): Control group: injected with 0.9 % saline (5 mL/kg, sc, daily for 9 days); Mechanical trauma: animals subjected to scratches (mechanical trauma of the right cheek pouch) on day 4 and treated with 0.9% saline (5 mL/kg, sc , from day 1 to 9); 5-FU: intraperitoneal injection of 5-FU (60 and 40 mg/kg, respectively, on days 1 and 2), subjected to scratches (mechanical trauma of the right cheek pouch) on day 4, and treated with 0.9% saline (5 mL/kg, sc, from day 1 to 9); amifostine (AMF): intraperitoneal injection of 5-FU (60 and 40 mg/kg, respectively, on days 1 and 2), subjected to scratches (mechanical trauma of the right cheek pouch) on day 4, and treated with 12.5, 25, or 25 mg/kg AMF, sc, from day 1 to 9.

Amifostine reduces inflammation and protects against 5-fluorouracil-induced oral mucositis and hyposalivation

Grape seed extract (GSE) was used as a positive control as it was shown to be non-toxic to IEC-6 cells in low doses and to protect against 5-FU (18).

Comparative effects of mistletoe extracts in combination with 5-Fluorouracil on viability of IEC-6 and Caco-2 intestinal epithelial cells

Pain related to treatment, side effects and cost can be determining factors in choosing a therapy.9 5-Fluorouracil (FU) is an antimetabolite that suppresses cell division and causes cell cycle arrest.10 Topical 5-FU is used in the treatment of warts but is not very effective.11 Intralesional injection of 5-FU permits higher drug concentrations throughout the lesion and previous study has shown it effectiveness in treatment of warts.12

Efficacy and safety of intralesional 5-fluorouracil in treatment of warts

Cytotoxic activity of extract was lower than fucoxanthin and 5-FU, while n-hexane and etyl acetate fraction seem higher than 5-FU but still lower than fucoxanthin.

Actividad Citotoxica del Extracto y la Fraccion Activa de Turbinaria decurrens Bory en la Linea Celular de Cancer de Colon HCT-116

5-FU was loaded into nanohydrogel samples by diffusion process.

Impact of Surfactant on the Pore and Particle Sizes of Copolymer (2-Acrylamido-2-Methylpropane Sulfonic Acid/Acrylamide) Nanohydrogels for Controlled Release of 5-Fluorouracil

A 34-year-old patient male patient was diagnosed with CA esophagus well differentiated keratinizing cell CA, he was admitted for the chemotherapy with cisplatin and 5-FU. He tolerated the treatment well, with no major complaints.

Cardiotoxicity associated with 5-flurouracil--A case series

The human fibroblasts were plated in 96-well plates and exposed to AgNPs, AgNPs + 5-FU, 5-FU, and Annona muricata.

Cytotoxic and Bactericidal Effect of Silver Nanoparticles Obtained by Green Synthesis Method Using Annona muricata Aqueous Extract and Functionalized with 5-Fluorouracil

This study evaluated the safety and effect of a single subconjunctival injection of BVZ combined with 5-Fu or MMC on the antiscarring effect of GFS and compared them with the use of uncombined agents in in vitro and animal experiments.

Combined Application of Bevacizumab and Mitomycin C or Bevacizumab and 5-Fluorouracil in Experimental Glaucoma Filtration Surgery

In this work, 5-fluorouracil (5-Fu) with the molecular size of 5.3 x 5.0 [[Angstrom].sup.2] was chosen as the guest molecules because it is a widely used drug molecule for the cancer treatment.

Fabrication of a Porous Metal-Organic Framework with Polar Channels for 5-Fu Delivery and Inhibiting Human Osteosarcoma Cells

[3] 11 5-FU 31 carbolpatin, FOLFORI Sugarbaker PH et al.

Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence

Licofelone (Cayman) and 5-Fluorouracil (5-FU, Sigma) were first dissolved in dimethyl sulfoxide (DMSO, Sigma) and diluted further with Dulbecco's modified Eagle's medium (DMEM, Sigma) to obtain required final concentrations.

Licofelone Inhibits Proliferation of Rat Hepatoma Cells

5-FU and S-1 are the most widely used fluorouracil and there are some differences between their components and pharmacological effects.

The Impact of the Expression Level of Intratumoral Dihydropyrimidine Dehydrogenase on Chemotherapy Sensitivity and Survival of Patients in Gastric Cancer: A Meta-Analysis