FLAP

(redirected from 5-Lipoxygenase-Activating Protein)
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AcronymDefinition
FLAPFddi Talk Link Access Protocol
FLAPFlight Application Software
FLAP5-Lipoxygenase-Activating Protein
FLAPForeign Language Assistance Program (US Department of Education)
FLAPFatal Light Awareness Program (Canada)
FLAPFamily Law Assistance Program (various locations)
FLAPFDDITalk Link Access Protocol
FLAPFour Letter Acronym Package (Introducing Microsoft .NET by David S. Platt)
FLAPFuel, Lubricants and Associated Products (UK)
FLAPFailure Location Analysis Program
References in periodicals archive ?
Hansson, "5-Lipoxygenase-activating protein: a potential link between innate and adaptive immunity in atherosclerosis and adipose tissue inflammation," Circulation Research, vol.
Ethier et al., "5-lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes," Journal of Experimental Medicine, vol.
ALOX5AP: arachidonate 5-lipoxygenase-activating protein, PTGS: prostaglandin G/H synthase.
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.
The synthesis of leukotrienes begins with the cleavage of arachadonic acid from cell membranes via the action of phospholipase [A.sub.2] Intracellularly, arachadonic acid is converted sequentially to 5hydroperoxyeicosatetraenoic acid (5-HPETE) and then to leukotriene [A.sub.4] ([LTA.sub.4]) by 5-lipoxygenase and 5-lipoxygenase-activating protein. [LTA.sub.4] is converted to leukotriene [C.sub.4] ([LTC.sub.4]) synthase, and is then transported into the extracellular microenvironment, where it is converted to leukotriene [D.sub.4] ([LTD.sub.4]) by the action of [alpha] glutamyltranspeptidase.
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