Critique: Exceptionally well written, organized and presented, "The Toad of Dawn: 5-MeO-DMT
and the Rising of Cosmic Consciousness" will be of special and particular interest to students of psychotropic substances upon the human brain.
Hundreds of thousands of people are undergoing the uncanny initiation into the tryptamine zone that is afforded by ayahuasca, vaporised or smoked DMT, 5-MeO-DMT and other substances.
The primary active components of the toad venom are the tryptamine alkaloids 5-MeO-DMT and 5-HO-DMT (bufotenin).
Among western users of 5-MeO-DMT in either synthetic or naturally occurring forms, references are sometimes made to Hindu and Buddhist concepts such as 'samadhi' and 'non-duality,' though invariably with an emphasis on the tremendous energies unleashed in these states.
It is generally accepted that the 5-MeO-DMT experience is qualitatively different from the N,N-DMT induced experience.
Three sources of DMT were tested: high purity synthetic 5-MeO-DMT, Bufo 5-MeO-DMT (an extract from the Sonoran desert toad venom, Bufo alvarius), and N,N-DMT from a natural extract of the Acacia Mimosa hostilis root bark.
20-30 mg for N,N-DMT; 2-5 mg for synthetic 5-MeO-DMT, and 30-40 mg for the Bufo 5-MeO-DMT material).
On the other hand, the relatively rare psychedelic substance DMT and its even more obscure relative 5-MEO-DMT were shown to produce quite widespread experiences, probably indicating the reliably powerful effect of these two substances.
Largely supporting Strassman's (2001) observations, DMT was widespread in inducing entity contact experiences and OBEs, although primarily to other dimensions, and like 5-MEO-DMT, DMT commonly gave the experience of dissolving into a universal energy.
Nevertheless, DMT, its close relative 5-MEO-DMT, and ayahuasca, the decoction in which DMT is found, all shared the same characteristic transpersonal features, although relatively more ayahuasca users reported contact with the plant/substance spirit than they did with the specific chemical compounds, as might be expected because the notion of sentience is more easily related to living organisms, though not exclusively (e.
the first time I took 5-MeO-DMt, I was with Terence McKenna in his home in Occidental with two other friends in 1985.
My 5-MeO-DMt journey experience with letting go and entering cosmic