TGN

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TGNTarragona (Catalonia, Spain)
TGNThesaurus of Geographic Names
TGNTrans-Golgi Network
TGNTotal Gaming Network
TGNThe Good News (Catholic Diocese of Kalamazoo newspaper)
TGN6-Thioguanine Nucleotides
TGNTask Group N (IEEE)
TGNTechnical Guidance Note (various organizations)
TGNTokyo Game Night
TGNThe Generations Network (various locations)
TGNThe Gamer Networks
TGNTrigeminal Neuralgia
TGNTelekom Global Net (T-Systems)
TGNTransport et Groupage du Nord (French: Transportation and Consolidation of the North)
TGNTrunk Group Number
TGNTasmanian Gaming Network
TGNTrade Games Now
TGNThe Gaming Nation
TGNTanzania Governance Noticeboard (Tanzania)
TGNTransporte de Gas del Norte
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References in periodicals archive ?
Objective: The aim of this study is to assess the relationship between TPMT activity and 6-thioguanine nucleotide (6-TGN) and 6-methylmercaptopurine ribonucleotide (6-MMPN) levels in patients with 11313 in clinical practice.
Differences in nucleotide hydrolysis contribute to the differences between erythrocyte 6-thioguanine nucleotide concentrations determined by two widely used methods.
Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients.
Analysis of 6-mercaptopurine, 6-thioguanine nucleotides, and 6-thiouric acid in biological fluids by high-performance liquid chromatography.
If patients with a homozygous deficiency of TPMT are given thiopurine derivatives at a standard therapeutic oral dosage, 6-thioguanine nucleotides will accumulate, usually within 4-6 weeks, to toxic concentrations.
Pharmacokinetics of 6-thioguanine nucleotides under i.v.
[1] Nonstandard abbreviations: 6-TGN, 6-thioguanine nucleotide; Me6-MP, 6-methylmercaptopurine; LC-MS, liquid chromatography--mass spectrometry; IR, infrared; NMR, nuclear magnetic resonance; and Me6-MPR, 6-methylmercaptoribonucleoside.
6-MP is further converted in the liver and gut to 6-thioguanine nucleotides, the pharmacologically active metabolites, by several enzymes, including hypoxanthine guanine phosphoribosyltransferase.