A1AR - What does A1AR stand for? The Free Dictionary
References in periodicals archive
The human A1AR
is palmitoylated at the C-terminal cysteine residue Cys309, and the palmitoylation level is not influenced by the agonist stimulation .
Indeed, the stimulation of a-adrenoreceptors (a1AR
) is predominantly associated with immunostimulatory effects on immune cells, for example, IL-1[beta] secretion by human monocytes and macrophages , which at-tributes to many chronic inflammatory disease states .
Glioma-induced MMP-2 activity in microglia could be significantly decreased by the A1AR
(an adenosine receptor subtype, found on microglia and neurons) , which might explain the fact that adenosine treatment leads to decreased extracellular protease activity and thereby exerts its inhibitory effects on glioma invasion.