(7.) Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ; A1c-Derived Average Glucose
In this paper we have utilized A1c-Derived Average Glucose (ADAG) study group algorithm to calculate the estimated average glucose (eAG) exposure in units of mmol/L.
The authors calculated mean glucose values from the CGM data from 90 patients with mean age of 76 years and with mean HbA1c values of 7.9% and calculated the ADAG eAG from the HbA1c values; the relationship between HbA1c and mean glucose values from the CGM data was different from the relationship between HbA1c and eAG indicating that A1c-Derived Average Glucose (ADAG) study group algorithm to calculate eAG may not accurately reflect average glucose in older adults .
A strong linear correlation between the levels of HbA1c and glycemia in the diabetic patients was found using the results from a big retrospective study, primarily the DCCT and the UKPDS [5-7], as well as from the studies of other authors [11-13], and it was the cause to perform the A1C-Derived Average Glucose (ADAG) study.
[14.] Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ, the A1c-Derived Average Glucose (ADAG) Study Group.
Translation of fasting glucose value to an approximate HbA1c level (adapted from the American Diabetes Association/ A1C-Derived Average Glucose
(4.) Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ, for the A1c-Derived Average Glucose
(ADAG) Study Group.
 Nonstandard abbreviations: Hb [A.sub.1c], hemoglobin [A.sub.1c]; ADAG, A1c-Derived Average Glucose
; eAG, estimated average glucose; DCCT, Diabetes Control and Complications Trial.
(5) The implementation of HbA1c results in terms of eAG will be discussed after the "A1c-derived average glucose
" (ADAG) results of the ongoing clinical trial are published.
If the ongoing "average plasma glucose study" fulfills its a priori specified criteria, an A1C-derived average glucose
(ADAG) value calculated from the A1C result will also be reported as an interpretation of the A1C results.