Our results also indicate that inflammation may suppress the expression of AANAT in the ovine pineal gland both at the transcriptional and posttranscriptional levels.
Stress was found to decrease nocturnal concentrations of melatonin in the pineal gland without affecting AANAT activity in nocturnal animals, such as rats , but was found to stimulate nocturnal secretion of melatonin in diurnal ungulate species .
2 DDC 150 forward dopa decarboxylase reverse NM_001009461 AANAT 154 forward aralkylamine reverse N-acetyltransferase KC290950 HIOMT 167 forward hydroxyindole reverse O-methyltransferase AY957615 TLR4 117 forward toll-like receptor 4 reverse NM_001206735.
Injection of LPS in the third ventricle increases AANAT
expression in cortex, hippocampus, and cerebellum but induces melatonin synthesis only in the cerebellum .
AANAT activity was measured by a radiometric assay (Parfitt et al.
TPH and AANAT activity results are expressed in pmol of radioactive product/200 mg of protein/h.
The AANAT assay also showed an activity pattern consistent with that observed for melatonin (Fig.
In the spider mite Tetranychus urticae th AANAT activity and melatonin content rose with hig exposure to ultraviolet radiation (Suzuki et al.
AANAT and TPH hav been previously described in different invertebrate taxa such as flatworms (Nishimura et al.