AARODAnesthesia-Assisted Rapid Opiate Detoxification
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On June 3, 2012, a man aged 30 years underwent AAROD. On extubation, he was unable to speak or follow commands.
On July 20, 2012, a man aged 46 years with a history of heroin, cocaine, and alcohol abuse underwent AAROD. Urine toxicology on that day revealed trace amounts of cocaine.
On August 19, 2012, a man aged 31 years underwent AAROD. The next day he experienced diarrhea, weakness, and blurry vision.
On August 23, 2012, a man aged 51 years underwent AAROD. Approximately 10 hours after extubation, while being monitored at the clinic, he experienced cardiac arrest with ventricular fibrillation.
On September 4, 2012, a man aged 26 years underwent AAROD. Approximately 30 minutes after naloxone infusion was initiated, he experienced cardiac arrest.
Anesthesia-assisted rapid opiate detoxification (AAROD) does not reduce subjective opioid withdrawal symptom scores more than traditional opioid detoxification modalities, but has been associated with a high risk for severe adverse events, including death.
Of 75 patients who underwent AAROD at a New York City clinic during January-September 2012, two died and five others experienced serious adverse events requiring hospitalization.
AAROD was developed during the 1980s with the goal of reducing the discomfort of withdrawal and thereby encouraging patients to enter substance abuse treatment.