ACDKArtefaktur Component Development Kit
ACDKAcquired Cystic Disease of the Kidney
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3,13,21) Additionally, the landmark study describing calcium oxalate deposition in RCCs with ACDK documented 1 CCRCC with crystal deposition, but this tumor was also associated with an ACD-RCC in the same kidney and the contralateral kidney.
Most cases (79%) also show intratumoral oxalate crystals, (6) a relatively specific feature that has been consistently observed only in ACD-associated RCC and not in other tumor types arising in the ACDK setting (Figure 1, D).
The mechanisms underlying the increased incidence of RCC in ESRD and ACDK have not been elucidated.