Concomitantly, it was essential that this new site would relate to the ACSR mission 'to acquire, store, and equitably distribute tumor tissues, biological fluids, and other biospecimens and associated clinical information from patients with HIV-associated malignancies to the scientific research community-at-large'.
The biobank's location in the immediate proximity of the laboratories of the Division of Anatomical Pathology at Tygerberg Academic Hospital facilitated the identification of qualified individuals who supported the establishment of the RBR infrastructure, and adoption of the manual of operations, standard operating procedures and bioinformatics platform of the ACSR. Besides discussions related to laboratory procedures for biobanks, and of the importance of preanalytical variables and controlling for them on research specimens, [12,13] selected best practices identified for more in-depth exploration are presented below.
What was new, however, was the ACSR mission of procuring specimens to be used by investigators at that institution as well as by individuals from outside the institution, outside SA, and even outside Africa.
The SSA RBR would be unique within the ACSR in that investigators desiring specimens from its collection would need to be African or collaborating with an African researcher.
The ACSR's mandate to collect specimens and make them available to any African or collaborating researcher approved through peer review was a new concept, and one requiring some discussion.
For this purpose, the SSA RBR has developed a marketing and promotion strategy that is based on established ACSR principles but specifically directed at various SA target groups.
As the steel twisted line in ACSR cable is made of ferromagnetism material, the steel strands can be magnetized adequately by rare earth permanent magnet.
The sensor based on MFL principle for detecting broken steel strands in ACSR cable is composed of magnetic source, magnetic conductor, data acquisition card, array of Hall elements and corresponding signal conditioning circuits.
Where, [G.sub.[delta]] is the magnetic conductance of the air gap between the inner surface of permanent-magnet and external surface of the steel strands in ACSR cable.
where, [[PHI].sub.m] is the flux of permanent-magnet (in Wb), [[PHI].sub.s] is the flux of steel strands in ACSR cable (in Wb), and the flux can be expressed as:
Then the magnetic induction density of steel strands in ACSR cable can be calculated as:
According to the analysis above, only if steel strands in ACSR cable are magnetized adequately, the leakage of the magnetic field fluxes to the surrounding atmosphere can be detected by the magneto-electric transducer such as Hall sensor.