The reduction in HbAlc through diet and exercise in the Early ACTID
study was comparable to the effect of sitagliptin and metformin among patients who had received no previous treatment for type 2 diabetes.
Fitzsimons, a doctoral student at the University of Bristol (England), and a member of the Early ACTID study team.
Activity volume in these Early ACTID participants was substantially lower than in overweight and obese nondiabetic participants in a prior University of Bristol study of daily physical activity patterns in 84 adults employed in sedentary occupations.
Baseline data from 155 men and 110 women enrolled in the Early Activity in Diabetes (Early ACTID
) study--a randomized, controlled trial comparing diet plus exercise with diet alone and usual care in adults with type 2 diabetes--were analyzed.