coli related hemolytic uremic syndrome [STEC-HUS]), and adults with a disease called generalized Myasthenia Gravis (gMG) who are anti-acetylcholine receptor (AchR
) antibody positive.
We did not detect antibodies against acetylcholine receptors (AChRs
) and muscle-specific tyrosine kinase (MuSK).
antibodies and muscle-specific tyrosine kinase antibodies were both negative.
Myasthenia Gravis (MG) is a disease characterized by time-varying muscular weakness and fatigue resulting from an autoimmune response to acetylcholine receptors (AChR
) in the postsynaptic neuromuscular region, generally due to the parasympathetic nervous system effect .
The NIHR said that based on its broad mandate, it affirms the following: First: The independence of the Judicial Branch in the Kingdom of Bahrain, in accordance with the national constitutional and legal framework, and in line with the principles contained in international and regional human rights instruments, in particular the International Covenant on Civil and Political Rights (ICCPR), the Arab Charter on Human Rights (ACHR
) and the Human Rights Declaration of the Gulf Cooperation Council (GCC) states.
Mostly, postsynaptic nicotinic acetylcholine receptors (AChR
) are targeted in MG (1).
We first tested pregnancies at risk of muscle-type acetylcholine receptor (AChR
) deficiency (mutations c459dupA and c753_754delAA) and cystic fibrosis (mutations AF508 and W1282X).
Myasthenia gravis (MG) is an antibody-mediated disease affecting the neuromuscular junction, caused by antibodies against the nicotinic acetylcholine receptor (AChR
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness which results from blockade of the acetylcholine receptors (AChR
) by antibodies and destruction of the receptors on the postsynaptic membrane.
As a second alternative, one can rely on the mechanisms established through the Arab Charter on Human Rights (ACHR
) and the Arab Commission for Human Rights.