ADDTCAlzheimer's Disease Diagnostic and Treatment Centers
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In group 1 patients (patients who are likely to be suffering from VaD), more patients fulfilled the ADDTC criteria than the NINDS--AIREN's for VaD.
The ADDTC criteria in comparison requires `a deterioration from a known or estimated level of intellectual function which is enough to interfere with the conduct of the patient's customary affairs of daily life, which is not limited to a single narrow category of intellectual performance'.
Overall a diagnosis of probable or possible VaD was made in 95% of group 1 patients using the ADDTC criteria, and in 80% of patients using the NINDS--AIREN criteria, suggesting that the ADDTC criteria are more sensitive than the NINDS--AIREN criteria although not necessarily specific.
In this group also, more patients fulfilled the ADDTC criteria for probable and possible VaD (11 patients), than the NINDS--AIREN criteria (five patients).
It remains to be seen however if the ADDTC criteria are more useful in making the diagnosis in these patients.
Both the ADDTC and NINDS--AIREN criteria are rather similar to the HIS in that they focus on the infarction concept of VaD, although it is possible that other mechanisms such as white matter ischaemia could be more important and common in causing VaD.