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ADH2alcohol dehydrogenase type 2
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The ADH2 gene promoter is repressed in the presence of glucose, since this metabolite inhibits the expression of the alcohol dehydrogenase regulator protein (Adr1) that is an activator of the ADH2 gene.
Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism.
The genotypes for the Alcohol dehydrogenase (ADH2, ADH3) and Aldehyde dehydrogenase (ALDH2) were determined through a collaborative study with The Indiana Alcohol Research Centre (ARC) of the Medicine Department of the University of Indiana using the TaqMan tests (Applied BioSystems, Foster City, CA).
In this study we analyzed archeological maize seeds associated with funerary remains from the site of San Lorenzo (1,500-700 BP (Munoz 2004)) and local modern maize landraces were analyzed for the short and highly variable region (microsatellite) present in the Adh2 gene.
Genetic polymorphisms of ADH2, ADH3, CYP4502E1 Dra-I and Pst-I, and ALDH2 in Spanish men: lack of association with alcoholism and alcoholic liver disease.
In the ADH2 treatment, the responses of genotypes were different again.
Alcohol dehydrogenases that perform most of the alcohol metabolism are homodimeric enzymes, which contain [alpha], [beta], and y subunits, being encoded by ADH1, ADH2, and ADH3 respectively.
Estos genes se encuentran cercanos en el cromosoma 1, pero las mismas plantas presentan secuencias mas parecidas a las de otros taxa del genero Zea para la adh2 (del cromosoma 4) y para cl (del cromosoma 9), sugiriendo una historia evolutiva compleja mediada por diferentes tipos de seleccion natural y patrones de flujo genico, que posiblemente sean comunes en la mayor parte de las angiospermas con polinizacion cruzada.
It's thought about a fifth of ethnic Jews have a rare variation on a gene called ADH2. Researchers have now linked this gene with a reduction in the likelihood of both drinking heavily and being badly affected by alcohol.
Human liver alcohol dehydrogenase: ADH Mompoiis results from genetic polymorphism at the ADH2 gene locus.
Eight primers (Table-1) of yeast were successful in amplifying DNA in the sample viz., ADH1, ADH2, ADH3, ADH4, ADH6, ADH5, ADH7 and ADH8 primers, Saccharomyces sppstrains used on wine production identifying variations at DNA level among the yeasts (Raton, 2004).