ADLTEAutosomal Dominant Lateral Temporal Lobe Epilepsy
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Mutations in the LGI-1/ Epitempin gene has been responsible for causing Autosomal Dominant Lateral Temporal Lobe Epilepsy (ADLTE), a partial epilepsy characterised by the presence of auditory seizures.
Autosomal dominant lateral temporal lobe epilepsy (ADLTE) is characterized by frequent partial seizures-two to five per month-that are associated with auditory or other sensory auras.
Tonic-clonic seizures also occur in the majority of ADLTE patients, but are infrequent, developing only about once a year.