Biotest US has transferred its ownership share in ADMA
to The Biotest Divestiture Trust, the parent company of Biotest US.
On this background, we hypothesized that ADMA
and SDMA levels might be predictive of the cardiovascular risk, all-cause mortality, and renal function of patients with anti-neutrophil-cytoplasmic antibodies (ANCA)-associated small vessel vasculitis (AASV) subjected to well-defined treatment regimens in four European Vasculitis Study Group (EUVAS) trials.
"This patent is the first of its kind for use of a polyclonal immunoglobulin preparation for treatment of respiratory infection and, in conjunction with three previously issued patents to ADMA
, further protects our proprietary immune globulin technology for the prevention and treatment of infection," commented Adam Grossman, president and CEO of ADMA
Regarding the analysis of L-arginine, ADMA
, and SDMA in human plasma, sample preparation by SPE using cation-exchange columns is the currently preferred approach [10-13].
The first methylation leads to the formation of monomethylarginine (MMA), while the second one can produce either symmetric dimethylarginine (SDMA) or ADMA
, according to the PRMT isoform involved in the methylation reaction .
Under the deal, Adma
will secure ownership and control of US based immune globulin manufacturing facility and an FDA licensed products portfolio with immediate and on-going commercial sales.
Asymmetric dimethylarginine (ADMA
), an endogenous NO synthase inhibitor, was reported to inhibit the mobilization, differentiation, and function of EPCs .
The conditions which increase the chances of developing CAD among T2DM patients are called risk factors, according to the American Diabetic Association.10,11 They include positive family history for CAD, age (>45 years for men, >55 years for post-menopausal women), gender (male>female), BP >140 systolic >90 diastolic, body mass index (BMI) >25Kg/m2, hypercholesterolaemia (Low High-density lipoprotein cholesterol [HDL-C] > low-density lipoprotein cholesterol [LDL-C]), triglycerides (TGs) >150mg/dl, fasting blood glucose (FBG) >125mg/dl and raised ADMA
is a strong predictor of impairment in endothelial function, there is lack of evidence in the literature as to whether increased levels of ADMA
correlate with ED in patients with CKD.
Conclusion: Our study reveals increased serum ADMA
levels in the patients suffering from type 2 diabetes mellitus without CAD when compared with the control group.
Umm Shaif, the first offshore field found in March 1958 by ADMA
, is one of the biggest in the Middle East - 20x15 km.
's initial plan was to pig the riser to make the riser free from hydrocarbon fumes.