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ADRB2Beta-2-Adrenergic Receptor (also seen as B2AR)
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References in periodicals archive ?
Our results showed for the first time that [[beta].sub.3]-AR is relevant for declarative memory acquisition and consolidation, since its absence in mice significantly impaired these processes despite an overexpression of Adrb2 in the hippocampus.
Considering the aforementioned facts we have decided to check if body mass and body composition, as well as metabolic variables observed in physically active participants will be modulated by the ADRB2, ADRB3 and ADRA2A gene polymorphisms.
However, several case-control studies conducted to investigate the association of ADRB2 polymorphism with asthma fail to reach a consensus.
In previous study, we conducted RNA-sequencing in skeletal muscle of six Thoroughbred horses before and after exercise, and found the fold-change value of ADRB2 gene was increased significantly after exercise (Park et al., 2012).
Anger suppression and adiposity modulate association between ADRB2 haplotype and cardiovascular stress reactivity Psychosomatic Medicine, 68 (2), 207-212.
(27) Polymorphisms in a number of genes such as uteroglobin (which has anti-inflammatory/immunomodulatory properties), TNF-[beta]*2, human leukocyte antigen (HLA) B54 (HLAB54), CFTR, lymphotoxin a (LTA), transforming growth factor [beta] (TGFB1), IL-1 receptor agonist (TL1RN), IL-22, [alpha]-1 antitrypsin, mesenchymal-epithelial transition (MET), and [beta]2 adrenoceptor (ADRB2) have also been observed in CRS patients.
[25] It was examined if there was association with the ADRB2 allele for the gene coding for the beta-2 adrenergic receptor and autism.
The genes displaying decreased expression also included epidermal growth factor receptor (EGFR: -5.57-fold), connective tissue growth factor (CTGF: -4.99-fold), adrenergic beta-2 receptor (ADRB2: 4.45-fold), transforming growth factor beta 1 (TGF-[beta] 1: -2.16-fold), bone morphogenetic protein 6 (BMP6: -3.49-fold), and tumor necrosis factor receptor superfamily member 11a (TNFRSF11A/RANK: -2.35-fold).
However, of more than 100 genes of potential interest, ADRB2 and ALOX5 are perhaps the most clinically relevant.
Ya se ha establecido que las variantes alelicas Arg16Gly y Gln27Glu del gen ADRB2, que codifica para el receptor beta-2 adrenergico, son marcadores farmacogeneticos.