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Two different analgesic testing methods were used in the current investigation with the objective to identifying possible peripheral and central effects of the AEMK. Using both hot plate test and acetic acid-induced writhing response in rats, it was observed that the plant extracts possessed analgesic effects against both models.
The AEMK also showed antinociceptive activity in the acetic acid test.
1.43 [+ or -] 0.08 2 Ibuprofen 50 mg/kg 0.50 [+ or -] 0.05 3 AEMK 100 mg/kg 0.79 [+ or -] 0.12 4 AEMK 300 mg/kg 0.89 [+ or -] 0.17 5 AEMK 500 mg/kg 0.75 [+ or -] 0.09 Group 2 h 3 h Average % no.
To determine any acute toxicity of AEMK, two groups of six rats each were used.
The results show that AEMK significantly increases mount frequency (MF) (p < 0.001) and decreases mount latency (ML) after 1 h 15 min and 3 h 15 min (p < 0.0001) compared to untreated rats.
The results of this test show that rats treated with AEMK have better mating performance, according to mating parameters.
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- Aemilian Way
- Aemilii Paulli
- Aemilius Papinianus
- Aemilius Paullus
- aemulationem vicini