Presently SAAG is not being used in our clinical practice, so this study was designed to compare the diagnostic sensitivity of SAAG and AFTP in ascites related to liver cirrhosis patients.
Estimation of albumin (g/l) was done on both serum and ascitic fluid by the Bromocresol green method17 and AFTP (g/l) was estimated by Biuret method18 on automated chemistry analyzer.
Sensitivity of SAAG and AFTP was calculated by comparing with ultrasonographic findings (gold standard) Sensitivity % = TP / TP + FN x 100.
Out of 73 patients, 71 (97%) were correctly identified as liver cirrhosis by SAAG at [greater than or equal to] 11 g/l while only 39 (53%) patients were correctly identified as cases of liver cirrhosis (transudate) at AFTP less than 25 g/l (pless than0.
The traditional classification of ascites into 'exudative' and 'transudative' based on AFTP has been used since long.
Results of the present study have also shown that AFTP at a cut off point of less than 25 g/l has a sensitivity of 53 % to label ascites of hepatic origin.
18 March 1983, AFT Office of the President, Box 64, Folder 64-16, AFTP, 1; Juan Williams, "White House Pushes for Tuition Tax Credit," Washington Post, 5 March 1983, sec.
Meet the Press," 29 May 1983, AFT Office of the President, Box 82, Folder: June-Miscellaneous, 1983, AFTP, 9; Ronald Reagan, "Interview with a Group of Senior Executives and Staff Members of the Wall Street Journal," 7 February i985, Public Papers of the Presidents of the United States: Ronald Reagan, 1985, Book I, 141.