AGTR1

AcronymDefinition
AGTR1Angiotensin II Type 1 Receptor
References in periodicals archive ?
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes.
Cao et al., "AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist," Proceedings of the National Academy of Sciences of the United States of America, vol.
Fimasartan (2-n-butyl-5-dimethylaminothiocarbonylmethyl-6-methyl-3-{[2-(1H- tetrazole-5-yl)biphenyl-4- yl]methyl}pyrimidine-4(3H)-one potassium salt trihydrate) represents a nonpeptide angiotensin receptor blocker, with selective AGTR1 blocking effects, which was approved by the Korean Food and Drug Administration in 2010 for the treatment of essential hypertension [9, 10].
Several components of the renin-angiotensin system, including angiotensin (ANG), angiotensin I converting enzyme (ACE), ACE2, and angiotensin II receptor type 1 and type 2 (AGTR1 and AGTR2), are shown in the subnetwork (Figure 3(d)).
* Specific anti-hypertensive drug selection based on genotypes such as ACE l/D, Corin, CYPII B2, HETE and CYP 4A11, AGTR1, and AGTAA.
AGT (M235T (rs699) and T174M (rs4762)), AGTR1 (A1166C (rs5186) and C573T (rs5182)], ACE [I/D (rs1799752) and G2350A (rs4343)), and CYP11B2 C-344T (rs1799998) polymorphisms previously shown to be significantly associated with kidney diseases in genetic polymorphism studies of Chinese Han populations [10, 16] were selected.
Gagnebin et al., "Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3; untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes," American Journal of Human Genetics, vol.
For example, angiotensin converting enzyme (ACE) gene, renin (RENIN) gene, angiotensin II receptor 1 (AGTR1) gene and genes involved in the feedback loops of lipid regulation e.g.
In general, individuals with DS exhibit lower blood pressure and lower angiotensin II type 1 receptor (AGTR1) protein levels than those without DS.
The impact of tagged single-nucleotide polymorphisms (tagSNPs) and inferred haplotypes in 12 candidate genes (ACE, ADRB2, AGT, AGTR1, ALOX15, EDN1, GRK4, PTGS1, PTGS2, TLR4, VEGFA, and VEGFB) on the relationship between residential proximity to major roadways and LVM was analyzed using multiple linear regression, adjusting for multiple potential confounders.
The gene, called AGTR1, caused normal breast cells to behave like cancer cells but the blood pressure drug losartan stopped them, the team at the University of Michigan found.