AICAR


Also found in: Medical.
AcronymDefinition
AICAR5-Aminoimidazole-4-Carboxamide Riboside
AICAR5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribofuranoside (AMPK Activator)
AICARAsian Institute of Communication and Research
References in periodicals archive ?
2000) Increased expression of GLUT-4 and hexokinase in rat epitrochlearis muscles exposed to AICAR in vitro.
Moreover, NOS activity normally induced by SW stimulation is blocked by the AMPK activator AICAR, whereas co-addition of cAMP elevators reverses such blockage while restoring GVBD (Stricker, 2012).
The team found that AICAR administration protected the mice from experiencing such contractions under heat stress.
It appears the activation of AMP kinase by AICAR fooled the body into believing it had exercised or, in the case of GW1516, exercised more than it actually had.
If you like exercise, you like the idea of more bang for your buck with GW1516 "If you don't like exercise, you love the idea of getting the benefits from a pill, as with AICAR.
Both of these drugs are anti-inflammatory, and they work by inhibiting an enzyme called 5-amidoimi-dazole-4-carboxamide ribonucleotide (AICAR) transformylase, resulting in AICAR accumulation.
Both of these drugs are anti-inflammatory, and they work by inhibiting an enzyme called 5-amidoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase, resulting in AICAR accumulation.
The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1.
Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients.