AICAR

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Acronym	Definition
AICAR	5-Aminoimidazole-4-Carboxamide Riboside
AICAR	5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribofuranoside (AMPK Activator)
AICAR	Asian Institute of Communication and Research

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References in periodicals archive ?

As mentioned, AQP1 was regulated by AMPK mediating AICAR. It also was reported that a gut peptide stimulating appetite, ghrelin decreased AMPK activation and increased metabolic enzymes transcript levels in the liver of rats (Kola et al., 2005).

Immunohistochemical Identification of AQP1 in Livers of the High-fat Diet Rats/Identificacion Inmunohistoquimica de AQP1 en Higados de Ratas con Dieta de Alto Contenido de Grasa

Marette, "The AMPactivated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle," FASEB Journal, vol.

Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health

In Sprague Dawley (SD) rats fed with a high-salt diet, the expression of p- AMPK was lower than that in the normal diet group but was increased by AICAR [19].

6-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPAR[delta] in HUVECs, HEK293, and Differentiated 3T3-L1 Cells

We focused on the effects of AMPK-mediated signaling and the NF-[kappa]B pathway as well as the MAPK-related signaling in cholestatic liver diseases and evaluated the protective role of AICAR against hepatic injury and fibrosis triggered by cholestasis-related inflammation.

AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-[kappa]B Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats

We previously reported that activation of endogenous AMPK by 2,4-dinitrophenol or AICAR significantly decreases the release of MCP-1 from mature 3T3-L1 adipocytes [13].

Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK

Next, we investigated whether increased AMPK activation by AICAR upregulated AMPK protein expression, with or without MDI treatment.

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux

To test if reversible acetylation of [epsilon]-amino groups on lysine residue plays a role in postmortem glycolysis, mice were intraperitoneally injected with AICAR, HAT, or HDAC inhibitors before slaughter and their effects on glycolysis in postmortem muscle were investigated.

Histone acetyltransferase inhibitors antagonize AMP-activated protein kinase in postmortem glycolysis

Mervaala, "AMPK activator AICAR ameliorates ischaemia reperfusion injury in the rat kidney," British Journal of Pharmacology, vol.

Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1

Kumagai, "Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles," Journal of Applied Physiology (Bethesda, Md.:1985), vol.

Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle

Young, "Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR," The American Journal of Physiology, vol.

Expressions Profiles of the Proteins Associated with Carbohydrate Metabolism in Rat Liver Regeneration

A previous investigation explained that the decrease in IL-1[beta] levels with MTX is due to the inhibitory effect of MTX on 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase (ATIC).

Evaluation of psoriasis severity and inflammatory responses under concomitant treatment with methotrexate plus micronutrients for psoriasis vulgaris: a randomized double blind trial

(2010) Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes.

Effects of nitric oxide synthase inhibition on fiber-type composition, mitochondrial biogenesis, and SIRT1 expression in rat skeletal muscle