Nevertheless, some studies have documented minor histopathologic differences between AIDS-KS and non-HIV-associated KS cases, namely, that mitoses and cellular anaplasia are more common in HIV-negative patients, whereas AIDS-KS lesions tend to display more extensive dissecting vessels.
In rare instances, AIDS-KS lesions may harbor concomitant pathologic findings, usually an opportunistic pathogen (eg, cryptococcosis, mycobacterial granulomas, or molluscum contagiosum).
A goal of our study was to determine the HHV-8 genotypes for a series of classic KS or AIDS-KS cases in Peru.
Two AIDS-KS mestizo patients (Figure 1) were thus found to be infected by typical E subtype HHV-8 strains: a 51-year-old man with a tumor on his neck and a 24-yearold man with multiple tumors on the upper limbs.
This study included planer, single photon emission computed tomography (SPECT) and neck pinhole (P)-SPECT in selected patients with KS (classic KS, AIDS-KS
and transplantation-associated KS).