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ALCAPAAnomalous Origin of the Left Coronary Artery from the Pulmonary Artery
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An 8-month-old female infant had coronary reimplantation at age 3 months for ALCAPA. Post-surgical ejection fraction showed early improvement with subsequent deterioration.
As a rather rare congenital anomaly, anomalous origin of the left coronary artery (LCA) from the pulmonary artery (ALCAPA) occurs in approximately 1 per 300,000 live births and represents 0.5% of all congenital heart disease cases.[1] The presentation and onset of symptoms typically occur shortly after the neonatal period as the pulmonary vascular resistance decreases and left coronary blood flow diminishes.
Transthoracic echocardiography (TTE) showed left ventricular ejection fraction (LVEF) of 40%, moderate mitral valve regurgitation (MR), and suspicion of ALCAPA that was confirmed by cardiac catheterization and coronary computed tomographic angiography (CTA) (figure 1).
Coronary artery anomalies are congenital abnormalities in the number, origin, course or termination of coronary arteries and are found in approximately 1% of the population.[1] Anomalous left coronary artery arising from the pulmonary artery (ALCAPA), or Bland-Garland-White syndrome is a rare congenital heart disease which accounts for about 0.25%-0.50% of congenital heart diseases.[2] ALCAPA is associated with high mortality in infants and is an uncommon diagnosis in adults.
ALCAPA is a rare congenital coronary abnormality also known as Bland-White-Garland syndrome.
Anomalous left coronary artery from pulmonary artery (ALCAPA) in infants: a 5-year review in a defined birth cohort.
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) syndrome or Bland-White-Garland syndrome, first described in 1933, [2] constitutes a rare congenital condition that affects 1 of 300.000 births.
It is even more unusual for someone to survive ALCAPA into adulthood.
In this article, a patient who reached the age of 11 without symptoms, referred because of a murmur heard on physical examination and diagnosed as ALCAPA as a result of catheterization-angiography performed upon findings on echocardiogram was presented to emphasize that patients with this anomaly can reach advanced ages without complaints.
Anomalous left coronary artery originating from the pulmonary artery (ALCAPA) is a rare coronary artery anomaly that affects 1 in 300 000 live births.' It was first described in 1886, but Bland, Garland and White described in 1933 the landmark case describing the clinical features linked with ALCAPA; hence it is also known as Bland-White-Garland syndrome.
Boy aged Now Callum has been diagnosed with Anomalous Left Coronary Artery from the Pulmonary Artery (ALCAPA) - a defect in which the left artery is connected to the wrong part of the heart.