A logistic regression model of PVT showed significance for several single parameters as continuous variables (Table 2(A)), but when all parameters were considered together, there was significance in the final model (Table 2(B)) for tumor multifocality, MTD, AFP, ALKP
, and albumin.
As shown in the table, no significant disparities between the groups were observed in laboratory parameters on admission and before MRCP, such as total bilirubin, ALKP
, ALT, AST, amylase, and lipase.
The report provides comprehensive information on the Alkaline Phosphatase (ALKP
or Phosphomonoesterase or Glycerophosphatase or Alkaline Phosphohydrolase or EC 184.108.40.206), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
Bowed knee was the dominant characteristic sign and bone related biochemical tests such as CA, P and ALKP
, LDH, and AST all decreased in concentration across the pediatric age range.
Immunoglobulin (IgG) alkaline phosphate enzyme (ALKP
) conjugated IgG (BIOREBA kit) and p'nitrophenyl phosphate (PNP) tablets were used for successful identification of PVY.
The serum samples at 35 d of age were also used for determination of glucose, total protein, albumin, cholesterol, triglycerides, glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and alkaline phosphatase (ALKP
) using commercially available kits (Biosystem S.A, Costa Brava, 30, Barcelona, Spain) according to manufacturer's instructions.
The restoration of serum levels of SGOT, SGPT and ALKP
, liver GSH status and reduction or inhibition of lipid peroxidation in liver of tBHP intoxicated mice after administration of ice-4 at dose of 250 mg/kg indicated its potential use for hepatoprotective activity.
This damage leads to rise in the levels of Serum Glutamic Pyruvate Transaminase (SGPT), Serum Glutamic Oxaloacetic Transaminase (SGOT), Alkaline Phosphatase (ALKP
), Lactic Acid Dehydrogenase (LDH), and Creatine Phosphokinase (CPK), as shown in various human [7-9, 11] and animal [2, 4] studies.
March (baseline) August # Total % # Total % Fail Fail ALKP
108 2372 4.55% 1 2826 0.04% CK 80 1332 6.01 % 8 1813 0.44% AST 73 2588 2.82% 19 3056 0.62% GLU 70 706 9.92% 0 690 0.00% TOTAL 331 6998 4.73% 28 8385 0.33% Reduction 91.54% September # Total % Fail ALKP
2 2659 0.08% CK 8 1849 0.43% AST 41 2904 1.41% GLU 0 665 0.00% TOTAL 51 8077 0.63% Reduction 84.59% (%) Figure 1.
We found that ALKP
activity was increased in both forms of BMP tested, BMP-2 and BMP-3, with BMP-2 generally exhibiting more expression.
 These factors probably lead to hepato-splanchnic hypoxia, a condition that is known to cause hepatocellular damage and rise in the levels of Serum Glutamic Pyruvate Transaminase (SGPT), Serum Glutamic Oxaloacetic Transaminase (SGOT), Alkaline phosphatase (ALKP
), lactic acid dehydrogenase (LDH) and creatine phosphokinase (CPK), as shown in various human [4-7] and animal  studies.