AMCPSAzienda Municipale Conservazione del Patrimonio e Servizi (Vicenza, Italy)
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While enactment of the EPA policy was the result of significant cooperation and collaboration amongst the parties involved, according to the EPA, only 10 AMCPs (< 5% of registered AMCPs) have been registered using the alternate framework since 2009 (personal communication, EPA OPP).
These are clearly situations where the reviewer was not familiar with the EPA OPP's acceptance of the alternate testing framework for AMCPs. Lack of awareness of existing approved non-animal testing strategies by some reviewers leaves industry less willing to submit these methods.
This led to collaboration between the EPA, seven AMCP companies, the Institute for In Vitro Sciences (IIVS), and the Accord Group in 2004.