After immunohistochemical examination the patient was diagnosed with AML MO, and classic 7+3 induction chemotherapy regimen involving cytosine arabinoside and idarubicin combination protocol was initiated.
Previous studies have demonstrated that PIH analysis of MPO is more sensitive than EC analysis of MPO.[7,18] These studies have demonstrated MPO immunoreactivity by PIH analysis of BM clot and core biopsy sections of AML MOs with MPO negativity by EC analysis.