The nine OxS parameters (hydroperoxides, AOPP
, RAP, thiols, uric acid, homocysteine, paraoxonase, arylesterase, and total FeOx) were evaluated as possible LOAD predictors, using simple logistic regression models.
The main anthropometric and biochemical serum parameters, including the levels of markers of oxidative damage to lipids (hydroperoxides) and proteins (AOPP
), ceruloplasmin, Lp-PLA2, and paraoxonase as well as TRAIL serum levels of the cohort of subjects (78% women) enrolled in the present study, are summarized in Table 1.
Results: Both partial and complete obstruction caused a significant increase in the serum creatinine, tissue MDA and tissue AOPP
9.1 [+ or -] 5.7 mmHg; P = 0.740), and aortic PP (AoPP
; 40.4 [+ or -] 14.0 mmHg vs.
Intravenous administration of 100 mg of iron after 3.5 hours of high-flux HD caused a 37% elevation in protein oxidation, as assessed by AOPP
To explore the regulatory role of AOPPs
on RAGE and AGE-R1 expression, we treated HMCs with various concentrations of AOPP
The interaction of ROS with proteins leads to the formation of advanced oxidation protein products (AOPPs
) and advanced glycation end products (AGEs) which constitute novel markers that provide information on the degree of oxidative damage in organism [64, 65].
Determination of AOPPs
has been based on spectrophotometric detection according to Witko-Sarsat et al.
As the results in table 2 show there are highly significant increases (p>0.001) in the mean value of serum lead and AOPP
in group A [Iraqi workers employed on the operation of diesel generators] when compared to group B [control group].
Blood samples were taken from athletes in order to determine the redox state, As the markers of oxidative stress we used advanced oxidation protein products (AOPP
) and malondialdechyde (MDA) and ImAnOx as marker of total antioxidative capacity, Blood samples were taken from an antecubital vein into Vacutainer test EDTA tube and stored immediately,
(22.) Abhishek Singh Nayyar, Mubeen Khan, "Serum total protein, albumin and advanced oxidation protein products (AOPP
)--implications in oral squamous cell carcinoma" Malaysian J Pathol 2012; 34(1): 47-52.
OS was evident in these patients as advanced oxidized protein products (AOPP
) and lipid hydroperoxides were elevated, whereas glutathione peroxidase activity and the ferric reducing antioxidant power (FRAP) were reduced.