tackles areas not addressed in a purely object-oriented OO approach to software development.
was diagnosed by exclusion and the patient was started on Naprosyn (250 mg three times daily).
The COSD for the CoinBox in Figure 5 consists of two AOSD
's for its two state dependent data members.
Ilaris is currently approved and marketed for the treatment of SJIA in the US and EU and for the treatment of AOSD
and the symptomatic treatment of refractory acute gouty arthritis in the EU.
The final diagnosis was AOSD
. In our case, there were no symptoms or signs of either high fever or debilitating joint although the FDG PET showed multiple FDG-avid lesions in the whole body scan.
Because urticarial rash is a hallmark of cryopyrinopathies, this case reinforces the autoinflammatory nature of AOSD
. Cryopyrinopathies are genetically determined diseases caused by mutations in NLRP3 (NLR family, pyrin domain containing 3) that manifest by cold-induced urticaria, periodic fever, and arthritis.
was finally diagnosed, based on the presence of pyrexia, polyarthralgia, skin rash, sore throat, leukocytosis, liver dysfunction, lack of RF, and the negative ANA titer.
According to the Yamaguchi criteria, the patient was finally diagnosed as AOSD
, and pulse steroid was initiated and administered for 3 days.
Aspect-Oriented Software Development (AOSD
)  proposes the separation of the crosscutting concerns of software systems into separate entities called aspects.
Aspect-Oriented Design Principles: Lessons from Object-Oriented Design, Sixth International Conference on Aspect-Oriented Software Development (aOsD
'07), Vancouver, British Columbia, Canada, March, pp.
and infections have apparent similarities such as acute onset, high fever, generalized lymphadenopathy, and elevated inflammatory markers, infectious triggers have been suggested for the cause of AOSD
Adult onset Still's disease (AOSD
) is a systemic inflammatory disease with unknown etiology resembling the systemic form of juvenile rheumatoid arthritis.