The questions aimed to determine whether the data summary accurately reflected and encapsulated the problems specific to establishing and managing the APHCRI CREs and whether the proposed strategies for preventing or managing problems were feasible.
A significant source of the problem was reluctance of the legal offices of some partner institutions to sign their partner agreement until certain conditions of the head agreement (the agreement between APHCRI and the administering institution) were changed.
APHCRI CREs faced with this problem generally negotiated specific arrangements with the institutions that were to host the successful applicant.
A second highly demanding challenge experienced by the APHCRI CREs related to the level and nature of investigator engagement with the CRE.
Specifically, the APHCRI CRE grant did not include investigator remuneration.