APLASAsian Symposium on Programming Languages and Systems
APLASAntiphospholipid Antibody Syndrome
APLASAlkaline Phosphatase-Labeled Anti-Salmonella (microbiology)
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APLAS is a leading enterprise offering dairy and agriculture products across Pakistan.
APLAS is characterized by systemic venous and arterial thrombosis, the latter occurring most often in the cerebral circulation, foetal loss, seizures, thrombocytopenia and pulmonary hypertension (2) Anticardiolipin antibodies (aCL) and lupus anticoagulant (LA) are two important antibodies found in this disease which cause both venous and arterial thrombosis (3).
Presence of Antiphospholipid antibodies lead to a hypercoagulable state by several distinct mechanisms like endothelial anticoagulant dysfunction, abnormalities of prostacyclin, antithrombin III, placental anticoagulant protein, protein C and protein S, and complement activation, any of which could lead to thrombosis and studies have shown that B2-GP1 may be the key immunogen in the APLAS (7).