We focused on 2 objectives: decide which APTM (APTM-11 or APTM-4) to use as a basis for harmonization, and demonstrate/ validate the suitability of the recalibrated results to meet the analytical specifications stated below.
Our attempt to harmonize commercially available TSH immunoassays began with a method comparison using samples from presumably healthy individuals (Phase I), in which we showed that recalibration using the APTM significantly increased the agreement of commercially available assays (29).
Eleven of the 14 assays had preharmonization median deviations within 10% from the APTM. The improved agreement after recalibration is shown by centering of the assays' differences (%) around zero difference from the APTM-4 targets, by the reduced differences (%) of the 15th and 85th centiles and the mean deviations (%) meeting the 7.8% bias specification with 95% confidence for 13 out of 14 assays.
 Nonstandard abbreviations: TSH, thyroid-stimulating hormone; RI, reference interval; IVD, in vitro diagnostic; C-STFT, Committee for Standardization of Thyroid Function Tests; APTM, all-procedure trimmed mean; TE, total error; LL, lower limit; UL, upper limit.
Officials from S8 Exhibition Inc., which is mounting the APTM, said in a briefing Thursday that this program was expected to help the Department of Tourism (DOT) generate higher tourism receipts, which are estimated to hit $6.5 billion this year.
For APTM, we are targeting the luxury travelers (who can spend) around P77,000 each, which is about 50 percent more than what your average tourist spends, said S8 Exhibition public relations officer Edwin L.
The target, Villanueva said, was for the APTM to generate as much as P7 billion in receipts within three years.
Yu said the first staging of the APTM was in May 2015, when the group was able to bring together 50 of the country's top luxury hotels, resorts, and destinations, and paired them with 100 international buyers from more than 30 countries.
Yu said the target was to have 100 buyers and 100 sellers for this year's edition of APTM.