AQP5Aquaporin5 (membrane channel protein found in salivary, tear, airway glands, cornea, & type 1 pneumocytes)
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Membranes were probed with primary antibodies (1:1000 for 1h at room temperature) against AQP5 (Abcam), SFTPC (Santa Cruz Biotechnology), HGF (Abcam), epidermal growth factor (EGF) (Elabscience), and vascular endothelial growth factor (VEGF) (Santa Cruz Biotechnology).
However, in the uremia, the location and expression of AQP5 and UTs in skin have not been studied.
showed that AQP5 is upregulated in kidney biopsies from DN patients [25].
Liu et al., "Gene expression of AQP1, AQP5 in Sjogren's syndrome model mice salivary gland, and the therapeutic effect of jiedu huayu herbs," New Journal of Traditional Chinese Medicine, vol.
RT-PCR analysis showed significant increase in AQP1 and AQP5 expression levels after treatment with both PI extract and MP, which might have caused the alleviation of pulmonary edema.
Fan et al., "Tanshinone IIA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and AQP5 expression in lung," Respiratory Physiology and Neurobiology, vol.
Using high throughput DNA sequencing methods they were able to pin down the underlying cause of the condition to mutations in the AQP5 gene, which encodes a water channel protein known as aquaporin 5.
Bir kornea epitel hucresi markeri olan su kanali proteini olan ve korneadan sivi uzaklastirmaya yarayan AQP5 ve gen disavurumu keratokonuslu kornealarda azalmistir.
Secretory glands and lung tissues apparently control fluid secretion through analogous regulation of AQP5. Lungs tissues, secretory glands such as the salivary and lacrimal, and ducts of the pancreas and bile are all known to contain AQP5.
basolateral) AQP5 Regula proporcion de agua Epitelios glandulares en secreciones en general glandulares Neumocitos tipo I Epitelio corneal AQP6 Localizada en membranas TC renal (c.
Rossi et al .[5] analyzed the AQP2 and AQP5 (uAQP5 and uAQP2) excreted in urine in 35 patients: 12 diabetic patients with normoalbuminuria and normal renal function, 11 with proteinuria nondiabetic nephropathy, and 12 with histological diagnosis and classification of DKD.
Takata, "Aquaporin-5 (AQP5), a water channel protein, in the rat salivary and lacrimal glands: immunolocalization and effect of secretory stimulation," Cell and Tissue Research, vol.