ARP3Actin-Related Protein 3
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References in periodicals archive ?
They say that this occurs because the ligand Delta, a protein that activates the Notch pathway, cannot travel properly within the sensory organ cells in the absence of Arp3 protein.
In the Arp3 mutants, there are significantly fewer microvilli, but the transport of Delta is compromised in Arp3 mutants, affecting the ability of Delta to activate Notch.
"Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis," Proceedings of the National Academy of Sciences of the United States of America 107(25): 11411-11416.