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ASK1Apoptosis Signal-Regulating Kinase 1
ASK1Arabidopsis Serine/Threonine Kinase1
References in periodicals archive ?
We have then analyzed transcription factors and found that NF[kappa]B and ASK1 were similarly activated at early time by both BCG MOIs and at 18 h, and using MOI 0.
24-26) In this study, MAPK signaling pathway molecules, including MEKK1, ASK1, MLK, NIK, MEK1/2, MEK4/7, ERK and JNK were significantly up-regulated in EV71-infected RD cells, which stimulated and induced the immune response of RD cells.
Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.
Many recent studies using inhibitor compounds have revealed that the components of the ASK1MAPK pathways have potential as therapeutic targets for the diseases in which ASK1 is involved.
MAPK pathways that are activated by MEKK1, TAK1, and ASK1 may link chemical signals to Nrf2 which then leads to the activation of ARE-dependent genes (60).
Knockdown of thioredoxin interacting protein attenuates high glucose-induced apoptosis and activation of ASK1 in mouse mesangial cells," FEBS Letters, vol.
The walls will be placed in ASK1 and ASK3 and will be part of the decor.
The authors also showed that ASK1 was an upstream activator of JNK1 (79).
The MAPKKK in JNK pathway includes MEKK1, MEKK2, MEKK3, and MEKK4, MLK, and ASK1 and MAPKK contain MKK4, MKK3, MKK6, and MKK7 [62, 63].
The binding of TBP-2 inactivates Trx, which breaks the Trx-ASK1 complex, allowing for the reactivation of ASK1 activity inducing apoptosis through activating JNK and p38 cascades [8].
Zhang, "Down-regulation of PTEN by sodium orthovanadate inhibits ASK1 activation via PI3-K/Akt during cerebral ischemia in rat hippocampus," Neuroscience Letters, vol.
In its inactive state, ASK1 is coupled to the reduced form of Trx 1 that induces its ubiquitination and degradation [166].