To determine the susceptibility and clinical significance of the NLRP3 inflammasome in ITP, we examined the SNPs of three NLRP3 inflammasome components and two inflammatory cytokines, including NLRP3 (rs35829419), CARD8 (rs2043211), NF-[kappa]B-94ins/del ATTG
, IL-18 (rs1946518), and IL-1[beta] (rs16944).
The aim of this study was investigate the possible effects of NF-[kappa]B1 -94 ins/del ATTG
and TNF-[alpha] (-308 G/A) gene polymorphisms on TNF-[alpha] serum levels and clinical parameters of sepsis in Turkish sepsis patients.
Ma, "GW25-e3074 94 ATTG
Insertion/Deletion Polymorphism of the NFKB1 Gene Is Associated with Coronary Artery Disease in Han and Uygur Women in China," Genetic Testing and Molecular Biomarkers, vol.
To test our hypothesis, we conducted a case-control study to investigate the association of NFKB1 -94 ins/del ATTG
polymorphism and NFKBIA -826C>T and -881A>G polymorphisms with the risk of lung cancer in a Chinese population.
The mean serum level of aTTG
in children with CD was 13 [+ or -] 3.1 (range: 1-75) U/mL; 43% (n = 12 out of 28) had serum aTTG
levels >10 U/mL.
Case-control studies that evaluated the association of the NFKB1 promoter -94ins/del ATTG
polymorphism with cancer risk and described in detail the genotype distributions of the polymorphism in cases and controls were included in this meta-analysis.
In general, these individuals have normal intestinal biopsies; they predictably react to gluten and have variable results with ATTG
, anti-gliadin, and anti-EMA titres [2,18,19, 23].
Characteristic Median, 5th-95th %, or n percentiles Age [years (median)] 34 19-64 Time of residency [years (median)] 25 3.0-53 Town of residency [SAC/other village (n)] (a) 154/34 BMI [kg/[m.sup.2] (median)] 25 19-35 Coca users (%) 53 Tobacco users (%) 3.7 Alcohol users (%) 0.0 Total U-As [[micro]g/L (median)] (b) 210 33-502 iAs (%) 12 4.8-23 MMA (%) 8.1 4.2-15 DMA (%) 80 65-89 N6AMT1 haplotypes (n) Haplotype 1: AATG (2/1/0 copies) (c) 30/81/77 Haplotype 3: ATTG
(2/1/0 copies) (c) 5/46/137 Haplotype 9: GTGT (0/1/2 copies) (c) 72/73/43 AS3MT haplotype (n) Haplotype 2: GCCATCAC (2/1/0 copies) (d) 90/75/21 (a) SAC: San Antonio de los Cobres; other villages: Santa Rosa de los Pastos Grandes, Pocitos, Olacapato, Cobres, Rosario de Lerma.
Astrata Group, Inc., (BULLETIN BOARD: ATTG
) is a US publicly listed company.
NF-[kappa]B-94 ins/del ATTG
promoter polymorphism was detected using the forward primer: TGC CTG CGT T-3, reverse primer: 5-GCT GGA GCC GGT AGG GAA-3' as well as probe 1: 5'-VIC-ACC ATT GAT TGG GCC-MGB-3' and probe 2: 5'-FAM-CGA CCA TTG GGC C-MGB-3' (Thermo Fisher Scientific, USA).
We also synthesized both internal primers with a 5' overhang (attg
) to omit reverse (3'[right arrow]5') chain elongation.