AUUOAcute Unilateral Ureteral Obstruction
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Acute unilateral ureteral obstruction (AUUO) is a clinical scenario commonly encountered due to obstructing stone, trauma, malignancy, and endometriosis.
(10) However, to the best of our knowledge, there are no reports of studies investigating the relative contribution of extravasated urine re-absorption to the overall increase of serum creatinine levels following AUUO. We believe that re-absorption of extravasated urine is a major contributor to the elevation in serum creatinine in cases of AUUO.
The induction of AUUO produced a significant rise in serum creatinine levels (Fig.
(3) Therefore, there is a strong case for investigating the exact mechanism responsible for plasma creatinine elevation in the setting of AUUO.