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ATFAquatics Training Facility (US Army)
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References in periodicals archive ?
Bolded sequences indicate the binding sequences of nuclear factor (NF-Y) (CCAAT), activating transcription factor 6 (ATF6), and XBP1 (CCACG).
Activating transcription factor 3 upregulated in cardiac fibroblasts after myocardial infarction
ATF4, activating transcription factor 4; eIF2[alpha], eukaryotic translation initiation factor 2; IDO1, indoleamine 2,3-dioxygenase 1; IFN, interferon; IFNAR, interferon alpha/beta receptor; IRF, interferon regulatory factor; ISGF3, interferon- stimulated gene factor 3; PD1, programmed death 1; PDL1, programmed death ligand 1; STAT, signal transducer and activator of transcription.
Abbreviations Arg1: Arginase 1 Ascll: Acyl-CoA synthetase long-chain family member 1 ATF3: Activating transcription factor 3 Atgl: Adipose triglyceride lipase BCAA: Branched-chain amino acids BCAT-1: Branched-chain aminotransferase 1 C.
ATF4: activating transcription factor 4; ATF6: activating transcription factor 6; IRE1: inositol-requiring enzyme 1; NRF2: nuclear factor (erythroid-derived 2-) like 2; P-eIF2: phosphorylated eukaryotic initiation factor 2; PERK: protein kinase RNA-like endoplasmic reticulum kinase; UPR: unfolded protein response; XBP1: X-box-binding protein-1.
ATF4, activating transcription factor 4; CHOP, C/EBP homolog protein; eIF2[alpha], eukaryotic translation initiation factor 2[alpha]; GADD34, growth arrest and DNA-damage inducible 34; GCN2, general control nonderepressible 2; HRI, haem-regulated inhibitor kinase; P, inorganic phosphate; PERK, protein kinase RNA-like endoplasmic reticulum kinase; PKR, double-stranded RNA-activated protein kinase; PP1, protein phosphatase 1.
DeRossi et al., "Suppressor role of activating transcription factor 2 (ATF2) in skin cancer," Proceedings of the National Academy of Sciences of the United States of America, vol.
After exposure to 10 [micro]M Cd[Cl.sub.2], the levels of activating transcription factor 4 (ATF4) were increased at 2 hr, with a further enhancement after that; this accumulation followed the transient but marked phosphorylation of the [alpha] subunit of eukaryotic translation initiation factor 2 (eIF2[alpha]) on serine 51.
Instead, mTORC1 contribution to purine synthesis occurs through the induction of the activating transcription factor 4 (ATF4) that in turn triggers methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) expression, a key component of the mitochondrial tetrahydrofolate cycle [12] (Figure 1(c)).
(2001 Identification of the G13 (cAMP-response-element-binding protein-related protein gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response.
A representative UPR-PERK component of activating transcription factor 4 (ATF4) was measured under the basal condition and ERS induction.
In addition to reducing translation, PERK-mediated phosphorylation of eIF2[alpha] also induces preferential translation of activating transcription factor 4 (ATF4), a transcription activator of the integrated stress response [32].
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