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AICDAActivation-Induced Cytidine Deaminase
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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme.
Blomberg, "Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase," Journal of Immunology, vol.
Landgraf et al., "MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase," Immunity, vol.
Abbreviations: AID: activation-induced cytidine deaminase; ASPP2: apoptosis-stimulating protein of p53 2; CagA: Cytotoxin-associated gene A; CBS: C-terminal binding sequence; CM: CagA multimerization; [CM.sup.AmI]: Amerindian type-I CM; [CM.sup.AmII]: Amerindian type-II CM; [CM.sup.E]: East Asian CM; [CM.sup.W]: Western CM; CSK: C-terminal Src kinase; EBV: Epstein-Barr virus; EMT: epithelial-to-mesenchymal transition; EPIYA: GluPro-Ile-Tyr-Ala; GAB: Grb2-associated binder; H.
Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.
Humby et al., "Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjoogren's syndrome," Journal of Immunology, vol.
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