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References in periodicals archive ?
Dexamethasone for acute asthma exacerbations in children: a meta-analysis.
Acute asthma exacerbations are largely preventable [2], and so are ED visits and hospitalizations for this reason [9, 20-22].
Another limitation is the lack of biological surrogate markers like cysteinyl leukotriene levels which have shown to be higher in acute asthma exacerbations. It is possible that these levels may have been reduced in the patients but did not translate into clinical effectiveness yet.
Previous studies have suggested a link between hMPV infection and acute asthma exacerbations in children, and between other respiratory viruses and exacerbations in children and adults, but this is the first to link hMPV infections with such exacerbations in adults, the investigators noted.
Stressor-linked alterations in the immune system may predispose to respiratory tract infections (35,36), which may trigger acute asthma exacerbations. Stress hormones influence immunoglobulin and cytokine expression and thus may increase a genetically predisposed individual's risk of developing asthma.
As salmeterol has a slower onset of action of 15 to 30 minutes, it should not be used for the treatment of an acute asthma exacerbation. Salmeterol is commonly used in pediatric asthma patients to prevent symptoms of nocturnal asthma and prevent exercise-induced asthma.
(8) Cincinnati Children's Hospital's evidence-based guidelines from 1998 also recommend MDI/S for children aged >1 year with acute asthma exacerbations? This guideline suggests using 4 to 8 puffs from a 90 [mu]g albuterol MDI at 1- to 2-minute intervals every 20 minutes for 1 hour, then every i to 4 hours subsequently.
Are metered-dose inhalers (MDIs) with holding chambers (spacers) more effective than nebulizers in delivering brochodilator medication in children with acute asthma exacerbations?
It offers no benefit for acute asthma exacerbations. For children, intravenous aminophylline may improve the clinical course of severe asthma attacks.
Some parents worry that the intense physical activity often associated with competitive sports at this level may precipitate acute asthma exacerbations. Suggested activity plans allow children with asthma to participate in activities of their choice.
Incorporating MDI use in the treatment of acute asthma exacerbations may help dispel the misconception of many patients that the nebulizer is a more "powerful" way of treating asthma.
Background Multiple studies have demonstrated that for acute asthma exacerbations, metered dose inhalers (MDIs) with attached valved spacers are as effective, if not more effective, than nebulizers.[1] Homemade spacers made from more readily available plastic bottles or polystyrene cups are sometimes substituted for conventional spacers.
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