Acute Kidney Injury
Network: report of an initiative to improve outcomes in acute kidney injury
The rate of acute kidney injury
was similar in both groups.
Urine neutrophil gelatinase-associated lipocalin as a marker of acute kidney injury
after kidney surgery.
Clinical profile of cases of acute kidney injury
in a tertiary care centre.
The acute kidney injury
network diagnostic were used to define the acute kidney injury8 while for acute respiratory distress syndrome Berlin definition was used.
(4) This was modified by the AKIN (Acute Kidney Injury
Network) and further developed in 2012 by KDIGO (Kidney Disease: Improving Global Outcomes).
Acute Kidney Injury
(AKI) is defined as transient decrease in kidney functions characterize by raise plasma creatinine with nitrogenous waste products leading to failure of fluid and electrolytes management.1 In pediatric population AKI is the one of the most important cause of morbidity and mortality.2 AKI may leads to long term problems due to limited residual kidney functions including proteinuria, chronic kidney disease (CKD) and hypertension.1-3 The incidence of AKI vary, poles part of the world include both developed and developing regions.
With wide application of percutaneous coronary intervention (PCI) technology in patients with coronary artery disease (CAD), contrast-induced acute kidney injury
(CI-AKI) has become one of serious complications, especially in those with acute coronary syndrome (ACS).
The Phase I trial will serve as a precursor to future Phase II clinical trials to test Metablok's efficacy for several indications, the first being the prevention of acute kidney injury
(AKI) often seen in patients undergoing cardiac surgery.
On admission for acute kidney injury
, initial pertinent laboratory results were remarkable for anemia (hemoglobin of 8.8 g/dL), acute kidney injury
(creatinine of 5.35 mg/dL and eGFR of 10 mL/min/1.73 [m.sup.2]), and elevated coagulation markers (international normalized ratio [INR] of 2.1, prothrombin time of 23.7 seconds, and activated partial thromboplastin time of 87.5 seconds).
Recent studies have demonstrated the role of semaphorin 3A in acute kidney injury
. For instance, semaphorin 3A was found to be a new early diagnostic marker of experimental and pediatric AKI (18).
Acute kidney injury
is a sudden decrease in kidney function with or without kidney damage, occurring over a few hours or days.