AZF

(redirected from Adrenal Zona Fasciculata)
AcronymDefinition
AZFAzoospermia Factor (Y chromosome gene)
AZFAzote Fertilisant (French chemical fertilizer plant)
AZFAdrenal Zona Fasciculata (neuroscience)
AZFAmerican Zionist Federation
AZFAdrenocortical Zona Fasciculata (cell biology)
References in periodicals archive ?
Within 8 days after surgery, adrenal zona fasciculata is well restored while reconstruction of the zona glomerulosa remains incomplete before day 30 of experiment [16].
In mice, Me[SO.sub.2]-DDE induces mitochondrial degeneration and cellular necrosis in the adrenal zona fasciculata. In this study, we used precision-cut tissue slice culture to examine local CYP11B1-catalyzed irreversible binding of Me[SO.sub.2]-DDE in the murine adrenal cortex.
In the search for target cells of chlorinated aryl methyl sulfones it was found that [sup.14]C-labeled Me[SO.sub.2]-DDE produces a high and specific accumulation in the adrenal zona fasciculata in mice (10).
CYP11B1 catalyzes the last step in this pathway but also, as mentioned, the metabolic activation of Me[SO.sub.2]-DDE in the adrenal zona fasciculata (12,30,31).
The application of tissue-slice culture proved very useful for examining bioactivation and toxicity of Me[SO.sub.2]-DDE in the mouse adrenal zona fasciculata ex vivo.