8 HLA B5801 allele was found to be strongly associated with adverse cutaneous drug reaction
caused by allopurinol among Han Chinese and Japanese patients.
Reduce the incidence of adverse cutaneous drug reactions
(ACDRs) by evaluating patients' historical, pharmacokinetic, and environmental risk factors.
Adverse cutaneous drug reactions
(ACDRs) develop in 2% to 5% of patients taking psychotropics (1) and can occur with all drug classes.
5] A recent study of severe adverse cutaneous drug reaction showed that delay of referral to the burn centre was confirmed as an important prognostic factor at the Cox regression multivariate analysis and had the greatest influence on mortality.
Adverse cutaneous drug reactions vary in their patterns of morphology and distribution.
Clinical study of adverse cutaneous drug reactions at a rural based tertiary care centre in Gujarat.
Pharmacovigilance study of adverse cutaneous drug reactions
in a Tertiary Care Hospital.
Adverse cutaneous drug reactions are seen worldwide4,5 and often initial presentation is trivial and benign but early identification of the condition, recognition of the culprit drug and its omission are the keystone in management and prevention of a more severe drug rash3.
Most adverse cutaneous drug reactions are not severe and very few are fatal2,8.
8) Amoxicillin was the most common drug causing adverse cutaneous drug reactions responsible for causing reaction in 7 cases followed by cotrimoxazole causing adverse cutaneous drug reactions in 6 cases.
The study concluded that adverse cutaneous drug reactions due to antibiotics are not a rare thing.