AGC

(redirected from Aggrecan)
Also found in: Medical, Wikipedia.
AcronymDefinition
AGCAutomatic Gain Control
AGCAutomotive Glass Cartridge (fuse)
AGCAutomatic Gain Control (US DoD)
AGCAssociated General Contractors
AGCAssociated General Contractors of America
AGCApollo Guidance Computer (NASA)
AGCAttorney-General's Chambers (Singapore)
AGCAgrochemicals
AGCAmerican Game Cartridges (Chandler, AZ)
AGCAshanti Goldfields Company (Ghana)
AGCAustralian Girls Choir (est. 1984)
AGCAutomatic Generation Control (electric utilities; power systems)
AGCArmy Geospatial Center (USACE)
AGCAssociate General Counsel
AGCAdvanced Ground Contact
AGCAdaptive Gain Control
AGCAutomatic Generation Control
AGCAtypical Glandular Cells
AGCAspartate/Glutamate Carrier
AGCAllegheny County Airport (airport code, Pittsburgh, PA )
AGCAsahi Glass Company
AGCAmador Gold Corp. (Canada)
AGCAdvanced Gastric Cancer
AGCAnnual Giving Campaign (various organizations)
AGCAdjutant General's Corps
AGCArt Glass Ceramic
AGCAutomatic Gauge Control (steel industry)
AGCAggrecan
AGCAggressive Content (behavioral health)
AGCAbsolute Granulocyte Count
AGCAttorney Grievance Commission
AGCAmerican General Corporation
AGCAssociation of Graphic Communications
AGCAssociation of Global Custodians (bank group)
AGCArkansas Geological Commission
AGCAmerican Greyhound Council
AGCAccelerated Global Connections (networking)
AGCAdjustable Gain Control (less common)
AGCAsia Global Crossing Ltd.
AGCAssociated Gospel Churches
AGCAlternative Grand Campaign (gaming)
AGCAcademic Governing Council (various organizations)
AGCAutomatic Guided Cart (material handling)
AGCAerojet General Corporation
AGCAgricultural Genetics Company (UK)
AGCAdvanced Graduate Certificate
AGCAusclad Group of Companies (Perth, Australia)
AGCAdult Gaming Centre (UK)
AGCAgriculture Canada
AGCAir-Ground Communications
AGCAustralian Gold Council
AGCAsian Greek Council
AGCGeneral Communications Vessel (US Navy)
AGCAt a Glance Chapter
AGCAssociation Généalogique de la Charente (French: Charente Genealogical Association; Cherente, France)
AGCAvid Gaming Community
AGCAdvantest Green Corporation (Japan)
AGCAfrican Ground Council
AGCAtlantic Gulf Communities
AGCArea Generation Control (electric utility)
AGCAdvanced Gas Centrifuge
AGCAgent Based Grid Computing
AGCChief Aerographer's Mate (Naval rating)
AGCAmphibious Group Command
AGCAntenna Gain Control
AGCArmy General Counsel
AGCAir Ground Co-Operative ATS (Air Traffic Services)
AGCAsociación Guatemalteca de Cardiología (Guatemala)
AGCAdaptive Gaussian Classifier
AGCAgreed Cost of Repairs
AGCAttack Group Commander
AGCAccess Gateway Controller
AGCAudiographics Conferencing
AGCAdvanced Graduate Certification
AGCAtari Games Corp.
AGCAnala Goat Company (Beasley, Texas)
AGCAlgebraic-Geometric Code
AGCActive Test Set Generator and Comparator
References in periodicals archive ?
Interleukin-ip (IL1P), Tumor Necrosis Factor alpha (TNF-a) and Interleukin-6 (IL6) are pro-inflammatory cytokines involved in the pathophysiology of OA, inducing overexpression of metalloproteinases (MMPs) and decrease synthesis of macromolecules, including aggrecan (POREE et al., 2008; KAPOOR et al., 2011).
Specifically, Parkinson and colleagues found increased levels of proteoglycans such as aggrecan in the tendon samples from patients that were used in this study (Parkinson et al., 2011).
Cartilage consists of a relatively small amount of chondrocytes embedded in abundant ECM, which contains numerous macromolecules, especially collagen fibrils and the large aggregating proteoglycan aggrecan (18).
After 21 days, adipocytes, osteocytes, and chondrocytes were detected using immunocytochemistry staining for FABP4, osteocalcin, and aggrecan, respectively.
Using these assays, we identified a donor, whose SFMSCs were similar to the BMMSCs in their proliferation and expression of CD29, CD44, and CD90 but exhibited a significantly higher chondrogenic potential based on the increased expression of aggrecan and type II collagen proteins [16].
With the advent of more sophisticated chromosomal testing techniques, including whole exome sequencing (WES), additional etiologies of ISS are being identified, most notably mutations in aggrecan (ACAN) and NPR2 genes [2, 3].
(3) After the loading fluid shear stress of 12 dyn x [cm.sup.-2] for 45 minutes, RT-PCR and Western blot assay were used to measure the expression of type II collagen, aggrecan, Cytokeratin 8, MAP-1, MAP-2, and MAP-4.
Chondroitin sulfate proteoglycans (CSPGs), including the lecticans aggrecan, versican, neurocan, and brevican, are joined to the hyaluronic acid polymer through "link" proteins including cartilage link protein (Crtl1).
It is also known for influencing fibril formation for collagens type I and II, accelerating fibrillogenesis and binding to aggrecan, mediating the organization of cartilage matrix for its load bearing function.
The density of aggrecan molecules is decreased with a resultant increase in cartilage water content.
(7) In trigger finger tendons, collagen type 1A1 and 3A1, aggrecan, and biglycan are up-regulated, while metalloproteinase inhibitor 3 (TIMP-3) and matrix metallopeptidase (3) (MMP-3) are down-regulated, a situation also described in Achilles tendinosis.
(20) The most abundant PG in articular cartilage and the ECM is aggrecan which is composed of a core protein, hyaluronan (HA), and several side chains of GAGs.