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References in periodicals archive ?
Serum biochemistry showed elevated blood urea nitrogen (BUN) (112.30 mg/dl), creatinine (3.5 mg/dl) and also showed normal total protein (7.0 g/dl), albumin (2.8 g/dl), alanine amino transferase (ALT) (34 IU/dl), alkaline phosphatase (ALP) (103 IU/dl), glucose (85 mg/dl), potassium (4.2 mEq/dl) and phosphorus (4.6 mg/dl).
Alanine amino transferase (ALT) and aspartate amino transferase (AST) were quantified in kinetic mode, while following the guidelines of the Institute for Reference Materials and Measurements (IFCC), in serum by means of commercial kits ALT / GPT Liquiform and AST / GOT Liquiform (Labtest, Minas Gerais, Brazil).
SAFETY study: alanine amino transferase cutoff values are set too high for reliable detection of pediatric chronic liver disease.
Aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) were determined by the method of Duncan et al.
Liver function tests were totally deranged with total bilirubin level being 9.6 mg% (direct bilirubin was 7.70 mg% and indirect bilirubin was 1.9 mg%), alanine amino transferase being 52 IU/L, aspartate amino transferase being 1045 IU/L, and alkaline phosphatase being 203 IU/L.
His initial laboratory values were as follows; haemoglobin: 10.7g/dl (normal: 14-18) white blood cells 3200/mm3 (normal:5000-11000) platelet:130.000/mm3 (normal: 130000-450000) prothrombin time 16.8 minutes aspartate amino transferase (AST): 126 U/L (normal: 0-35) alanine amino transferase (ALT): 102 U/L (normal:0-45) albumin: 2.6 g/dl (normal: 3.5-5.2) globulin: 3.4g/dl (normal: 2.3-3.5) alpha- fetoprotein (AFP): 61 ng/ml (normal: 0-13) His hepatitis B surface antigen and delta hepatitis antibody were also positive.
Erythrocyte sedimentation rate was 48mm/h, CRP was 23mg/L (nR: 0-5mg/L), aspartate amino transferase (AST) was 58 U/L, alanine amino transferase (ALT) was 38 U/L, blood urine nitrogen (BUN) was 14 mg/dL, and serum creatinine (SCr) was 0.6 mg/dL.
Meanwhile, the drug appears to be dose-related acts but on the other hand no significant change in alanine amino transferase (ALT) and malondialdehyde (MDA) in this study were consistent with the expected results [17,15] at least with these doses.
Blood samples drawn on day 0, 3, 7, 10 and 27 respectively were used to measure serum enzymes Aspartate Amino Transferase (AST) and Alanine Amino Transferase (ALT).Both the enzymes showed reduction in the early period of drug administration then started to elevate from day 10 of treatment.
In the current investigations we observed that ethanol produced hepatotoxic effects in rats, as manifested by significant increase in the serum levels of Alanine Amino Transferase (ALT) and Gamma Glutamyl Transaminase (GGT) in group B, when compared to those in group A (p less than 0.05); this may be because of oxidative stress.
Marked elevations of liver tests (aspartate amino transferase or AST and alanine amino transferase or ALT) suggest inflammation of the liver (such as viral hepatitis).